Postprandial Mineral Metabolism and Secondary Hyperparathyroidism in Early CKD

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Postprandial mineral metabolism and secondary hyperparathyroidism in early CKD.

Normophosphatemia and normocalcemia are maintained in chronic kidney disease (CKD) by increased levels of fibroblast growth factor-23 (FGF-23) and parathyroid hormone (PTH), but the stimuli for secretion of these hormones in early CKD are incompletely understood. Most human physiologic studies have focused on random or fasting measurements of phosphorus, calcium, FGF-23, and PTH, but in this st...

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[Prevention and treatment of secondary hyperparathyroidism in CKD].

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FGF23 and mineral metabolism, implications in CKD-MBD.

Correspondence: Mariano Rodríguez Servicio de Nefrología. Hospital Universitario Reina Sofía. REDINREN, IM IBIC, Córdoba. [email protected] The regulation of mineral metabolism is achieved trough a complex interaction of hormonal factors and target organs. Before the discovery of FGF23 we believed that the regulation of serum calcium and phosphate was mainly the result of...

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Genetic African Ancestry and Markers of Mineral Metabolism in CKD.

BACKGROUND AND OBJECTIVES Disorders of mineral metabolism are more common in African Americans with CKD than in European Americans with CKD. Previous studies have focused on the differences in mineral metabolism by self-reported race, making it difficult to delineate the importance of environmental compared with biologic factors. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS In a cross-sectio...

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Bone Mineral Density and Secondary Hyperparathyroidism in Pulmonary Hypertension

BACKGROUND Low bone mineral density (BMD) is common in chronic lung diseases and associated with reduced quality of life. Little is known about BMD in pulmonary hypertension (PH). METHODS Steroid-naïve patients with PH (n=34; 19 idiopathic, 15 chronic thromboembolic) had BMD measured by DXA at the time of diagnostic right heart catheterization. Exercise capacity, quality of life and various p...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2008

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.2007060673